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COMPLEMENT C3B INACTIVATOR PROTEINS
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DeCS
Descriptor
English
:
Complement C3b Inactivator Proteins
Descriptor
Spanish
:
Proteínas Inactivadoras del Complemento C3b
Descriptor
Portuguese
:
Proteínas Inativadoras do Complemento C3b
Tree Number:
D12.776.124.486.274.920.325
Definition
English
:
Endogenous
proteins
that inhibit or inactivate
COMPLEMENT C3B
. They include
COMPLEMENT FACTOR H
and
COMPLEMENT FACTOR I
(C3b/C4b inactivator). They cleave or promote the cleavage of C3b into inactive fragments, and thus are important in the
down-regulation
of
COMPLEMENT ACTIVATION
and its cytolytic sequence.
Indexing Annotation
English
:
DF: C3B INACT
Pharmacological Action:
Complement Inactivating Agents
History Note
English
:
2006 (1978)
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DU
diagnostic use
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
22142
Unique Identifier:
D003180
Occurrence in VHL
:
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